Ronaldo reached half a century of Serie A goals in just 61 matches as league leaders Juve defeated slumping Lazio 2-1 in Turin on Monday.
The five-time Ballon d’Or winner scored twice in the space of three second-half minutes to put Juve on the cusp of their ninth successive Scudetto.
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Real Madrid and Manchester United great Ronaldo also became the first player to score 50 or more goals in Serie A, La Liga and the Premier League.
Ronaldo has scored 30 Serie A goals in 30 appearances to top the charts alongside Immobile with four matches remaining.
“As I’ve always said, talking about an opportunity to win is like a chance to score a goal. It means nothing unless the objective is achieved,” Sarri said.
“We need to get another four points, every point is difficult at the moment playing every three days, so we’ve got to keep focused.